MersV1, France, Analysis, bibRecord, 000172

Current tools for the identification of miRNA genes and their targets

Identifieur interne : 000172 ( France/Analysis ); précédent : 000171; suivant : 000173

Current tools for the identification of miRNA genes and their targets

Auteurs : N. D. Mendes [France, Portugal] ; A. T. Freitas [France] ; M.-F. Sagot [France]

Source :

Nucleic Acids Research [ 0305-1048 ] ; 2009.

RBID : ISTEX:98638AF5D9974F9BC77F3279DE142725EDE6B340

Abstract

The discovery of microRNAs (miRNAs), almost 10 years ago, changed dramatically our perspective on eukaryotic gene expression regulation. However, the broad and important functions of these regulators are only now becoming apparent. The expansion of our catalogue of miRNA genes and the identification of the genes they regulate owe much to the development of sophisticated computational tools that have helped either to focus or interpret experimental assays. In this article, we review the methods for miRNA gene finding and target identification that have been proposed in the last few years. We identify some problems that current approaches have not yet been able to overcome and we offer some perspectives on the next generation of computational methods.

Url:

https://api.istex.fr/ark:/67375/HXZ-RLQ12DJ4-Z/fulltext.pdf

DOI: 10.1093/nar/gkp145

Affiliations:

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to stream France, to step Extraction: 000172

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ISTEX:98638AF5D9974F9BC77F3279DE142725EDE6B340

Le document en format XML

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Current tools for the identification of miRNA genes and their targets

Current tools for the identification of miRNA genes and their targets

Source :

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri